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Isaiah 13:6

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 6 Wail for the day of the LORD is at hand; it shall come as destruction from the Almighty.1

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1 The Day of the Lord against Babylon is not the physical Babylon; instead it is the pride and self-righteousness of man in general, and in particular as it is expressed in the false religions of the world. When comparing the description of the events, they parallel what is described in Matthew, Mark, and Luke, where Jesus is recorded saying all the end times prophesies would be fulfilled before the generation of 2000 years ago died, (click here to see all). Since we know that no one who lived 2000 years ago, could possibly still be alive, we understand that it is a personal experience for all men.
See Francis Howgill's excellent writing for the details of the Day of the Lord.
The Day of the Lord and the Second Appearance of Jesus are the same. Jesus told us more of his appearance: For the Son of man shall come in the glory of his Father with his angels; and then he shall reward every man according to his works. (Not just a particular generation.)
Some standing here shall not taste death till they see the Son of Man coming in His kingdom. Mat 16:27-8,Mar 8:38,9:1,Luk 9:26-27

Those not purified, to see Jesus' coming in them before death, see him as they die, as all peoples, all nations, all generations do.
Behold, he comes with clouds; and every eye will see him, and also those who pierced him; (also, the Jews 2000 years ago)
and all the peoples of the earth shall wail because of him. Even so, Amen. Rev 1:7.
2000 years ago, to the Jewish High Priest and the Pharisees at his trial, Jesus said..
you will see the Son of Man sitting at the right hand of the Power, and coming on the clouds of heaven.  Mark 14:62

This is not a particular generation in our time or later. (See Howgill for more on those not purified).
Heaven appears to our spiritual eye as in a mist or in clouds — so, his coming is on the clouds of heaven, within the hearts of purified believers.
We also have the record of Daniel seeing the Son of Man coming on the clouds in great glory: I saw in the night visions, and, behold, one like the Son of man came with the clouds of heaven.
He will appear a second time, not to bear sin, but to bring salvation to those who are waiting for him. Heb 9:28.
Notice he appears to bring salvation. But he doesn't bring salvation to the whole world — only to those waiting for him.
Neither is his appearance to the whole world, only to those who are waiting for him, and who love him by obeying him.
Salvation occurs when He appears within to bring salvation to those who have waited..listened..heard, and obeyed him — those who love him, and who are kept by the power of God through faith unto salvation ready to be revealed in the last time. 1 Pet 1:5